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Instead, a focus on holistic management strategies, including a balanced diet, tailored physical therapy, and lifestyle modifications, can provide more meaningful support for individuals with EDS

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Nrf2 has been demonstrated to affect BBB integrity by regulating the expression of BBB endothelial TJ proteins such as ZO-1 and OCLN (207)

These protocols also promote telomere elongation, reduce DNA damage, and assist in cellular adaptation